Person with closed eyes embraced from behind, surrounded by dreamy pink and purple light effects

Online gender-affirming hormone therapy and everyday care

Plume Clinic is an online gender-affirming care clinic providing hormone therapy and everyday healthcare for trans and gender non-conforming folks. Meet with licensed clinicians, get prescriptions online, and access ongoing support, all from your phone.

Your People. Your Place.​

Only $5/Month for unlimited access

Join Now

*Must be 18+ (or 19+ if residing in Nebraska or Alabama) to join.

Prism logo
Person in with long hair interacting with their smartphone

How Plume Clinic works

1

Choose your membership

2

Intake & scheduling

3

Join Prism, our online community

4

Meet with your provider​

5

Begin your treatment​

Essentials for your gender journey

Make accessing transgender healthcare and hormone therapy more affordable.

Care from clinicians specialized in transgender health & transition care

Male-to-female (MTF), female-to-male (FTM) and non-binary hormone therapy appointments available in days

Gender-affirming healthcare right from your phone

Access our exclusive online community, support groups, and trans resources

Gender-affirming care that goes beyond hormones

No matter where you are in your transition, we partner with you to address your unique health needs.

For your gender journey and more — we’ve got you.

Person in a white floral blouse holding daisies against a clear sky

Check out our FAQs

How do I start gender-affirming hormone therapy?

You can start your male-to-female (MTF) or female-to-male (FTM) gender transition with gender-affirming hormone therapy. You start by speaking with a qualified healthcare provider who understands your transition goals and will review your medical history. This may include discussing hormone therapy, mental health support, or other aspects of care.

With Plume, you can start gender-affirming hormones online. No therapist letter or insurance required!

You can get a gender-affirming hormone therapy prescription online by meeting virtually with a licensed medical provider who is qualified to prescribe treatment.

Plume provides gender-affirming hormone therapy through secure online appointments. After signing up, you’ll meet with a licensed clinician who will guide you through your options and create a personalized care plan based on your needs. If hormone therapy is appropriate for you, your provider can prescribe medication and arrange any necessary lab work without requiring an in-person visit*.

*Florida law requires informed consent forms to be signed in person to receive treatment. Learn more here.

Gender-affirming care includes medical and supportive services that help people align their physical characteristics and overall well-being with their gender identity. 

This can include hormone therapy such as testosterone or estrogen, mental health support, lab monitoring, and ongoing guidance from experienced clinicians. Gender-affirming care can also include services like voice support, hair removal, and surgical referrals, depending on your goals. The specific care you receive depends on your needs and what feels right for you.

Plume is an online gender-affirming care clinic that provides medical care for trans and nonbinary people through licensed clinicians.

Members can access trans care entirely online, including consultations, prescriptions, and ongoing support. After joining, you’ll meet with a provider who will create a personalized care plan and continue supporting you throughout your gender transition.

Yes. Plume is a legitimate healthcare provider offering gender-affirming care through licensed clinicians specialized in transgender healthcare. All care is delivered by qualified medical professionals who follow established clinical guidelines. Plume provides ongoing support, prescriptions, and lab coordination through a secure online platform.

Yes. Plume providers are licensed healthcare professionals, including doctors and nurse practitioners. They are experienced in gender-affirming care and are qualified to prescribe hormone therapy, order lab tests, and provide ongoing medical support.

Stay Connected

Get content about the trans experience right in your inbox

In order to provide healthcare services to you and give you medically appropriate care, we are required to get a recent blood pressure reading. You can get your blood pressure read for free at many pharmacies, go to your primary care doctor, or you may purchase a blood pressure cuff online.