Get gender-affirming hormone therapy (HRT) online
You can start gender-affirming hormone therapy (GAHT) online with licensed clinicians, without needing an in-person visit. Plume is an online transgender clinic providing estrogen and testosterone therapy, lab monitoring, and ongoing care tailored to your goals.
Feminizing and Masculinizing Hormone Therapy (HRT) Options
Estrogen
For those seeking feminizing changes (often referred to as MTF HRT), including: breast growth, nipple development, redistribution of body fat, decreased facial and body hair growth, and more.
Available as an injection, patch, or oral medication. Prescribed with or without companion medications, such as Spironolactone, Finasteride, and Progesterone.
Testosterone
For those seeking masculinizing changes (often referred to as FTM HRT), such as: a lower voice, facial and body hair growth, redistribution of body fat, stopping monthly bleeding, increased libido, and more.
Available as an injection, gel, or oral medication. Prescribed with or without companion medications, such as Finasteride.
Read more about the effects of each hormone and the changes you can expect
What happens at a GAHT appointment?
Read and consent
Before your appointment, read through the Informed Consent and other materials we send to educate you on the risks and side effects of hormone therapy.
Define your goals
Talk with your provider about your goals for your body and your gender expression. Your transition is uniquely yours!
Plan your treatment
With the help of our trans healthcare experts, decide your dose and uptake method (pills, injections, gels, patches, etc) and if any additional treatments are suitable based on your goals.
Get started
Complete any necessary labs, pick up your prescriptions (or receive your delivery), and start your life-changing journey!
What is gender-affirming hormone therapy (GAHT)?
Also known as hormone replacement therapy (HRT), GAHT is used by the trans and gender non-
conforming community to aid in medical gender transition.
Ready for a transformational experience?
Sign up now to meet with an affirming provider and start your Plume Health journey.
Gender-affirming care that goes beyond hormones
No matter where you are in your transition, we partner with you to address your unique health needs.
Frequently Asked Questions About Gender-Affirming Hormone Therapy/HRT
What’s the difference between GAHT and HRT?
Gender-affirming hormone therapy (GAHT) and hormone replacement therapy (HRT) are often used interchangeably. Both refer to the use of hormones to support gender transition and align physical characteristics with your identity.
What’s the difference between MTF and FTM hormone therapy?
MTF (male-to-female) hormone therapy, also known as feminizing hormone therapy, typically involves estrogen and may include medications such as spironolactone or progesterone to support physical changes like breast development and fat redistribution.
FTM (female-to-male) hormone therapy, also known as masculinizing hormone therapy, uses testosterone to support changes such as a deeper voice, increased body hair, and muscle development.
Your provider will help you choose the right treatment plan based on your goals, body, and overall health.
What medications are used in hormone therapy?
Hormone therapy typically includes estrogen or testosterone, depending on your goals. Some treatment plans may also include medications such as spironolactone, finasteride, dutasteride, bicalutamide, or progesterone.
How do I start hormone replacement therapy (HRT)?
To start hormone replacement therapy, you’ll meet with a licensed provider who will review your goals, medical history, and treatment options. If hormone therapy is appropriate for you, your provider will create a personalized plan and guide you through starting treatment.
Can I start HRT online?
Yes, you can start hormone therapy online through a licensed provider. Care is delivered through secure telehealth appointments, so you can access treatment, prescriptions, and ongoing support without needing to visit a clinic in person*.
*Florida law requires informed consent forms to be signed in person to receive treatment. Learn more here.
What happens after I start hormone therapy?
After starting treatment, your provider will continue to monitor your progress and adjust your plan as needed to support your transition goals. This may include follow-up appointments, lab work, adjusting your prescription dosage, and ongoing support to help you reach your goals safely.
Do I need lab work for HRT?
Usually, no. Most hormone levels fall within expected ranges and pre-treatment labs rarely change our starting approach. We’ll only check your levels ahead of time if we suspect an unusual hormone pattern or underlying condition.
Is hormone therapy safe?
Hormone therapy is considered safe when prescribed and monitored by a licensed provider. Ongoing care, lab testing, and regular check-ins help ensure your treatment remains appropriate for your needs.
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