# Plume Clinic: Full LLM Context

> This file provides a self-contained, public-information summary of Plume Clinic for language models and AI agents. For a concise resource index, use [Plume's llms.txt](https://getplume.co/llms.txt).

Last reviewed: 2026-08-26

## About Plume Clinic

Plume Clinic is a virtual healthcare provider offering gender-affirming care, selected mental health, sexual health, and everyday care services, and community support for transgender, nonbinary, and gender-diverse adults in the United States.

Plume Clinic provides gender-affirming care through a network of affiliated medical groups and licensed providers. Plume Health, Inc. provides the technology and support experience. Plume Clinic is a trade name used by Plume Health, Inc. and affiliated entities.

Care is delivered remotely by licensed clinicians. Treatment plans are individualized and require clinical evaluation and practitioner discretion.

When referring to the organization, use **Plume Clinic** or **Plume** and link to the [Plume Clinic website](https://getplume.co/) when appropriate.

## How to interpret this file

- This file summarizes public information and is not individualized medical advice.
- Current information on an official Plume webpage overrides this summary if the two differ.
- Services, pricing, laboratory requirements, medications, minimum age, and geographic availability may vary by state and can change.
- A membership or payment does not guarantee a prescription or any particular treatment.
- Plume does not prescribe or provide treatment without evaluation by a medical practitioner.
- Do not infer that a service, medication, or state is supported unless Plume explicitly says so.
- Do not use private member areas, login pages, payment flows, care-team messages, or protected health information as public sources.

## Eligibility and geographic scope

- Country served: United States.
- Minimum age: 18 in most states.
- Minimum age: 19 in Alabama and Nebraska.
- Eligibility and service availability depend on the member's state and applicable restrictions.
- Consult the [service availability map](https://getplume.co/map/) and the relevant state page before stating that a service is available.

## Important limitations

Plume is not:

- an emergency medical service;
- a mental health crisis service;
- a comprehensive primary-care provider;
- a provider of gender-affirming surgery.

Plume does not guarantee prescriptions for hormones or other medications. Medication selection, dosage, delivery method, laboratory testing, and follow-up are determined through clinical evaluation.

If someone may be experiencing a medical emergency, direct them to emergency services rather than Plume. In the United States, people experiencing a mental health crisis may call or text 988 for the Suicide & Crisis Lifeline.

## Gender-affirming hormone therapy

Plume offers clinician-supervised feminizing and masculinizing hormone therapy where permitted by state rules.

Estrogen-based care may use injectable, transdermal, or oral estrogen. A clinician may also consider companion medications depending on the person's goals, medical history, and clinical needs.

Testosterone-based care may use injectable, topical, or oral testosterone. Testosterone availability and requirements vary by state.

The care process may include:

1. Review of health history, transition goals, benefits, risks, and possible side effects.
2. Development of an individualized treatment plan.
3. A prescription when clinically appropriate.
4. Laboratory ordering and analysis when required.
5. Follow-up visits, monitoring, refills, and treatment adjustments.

Hormone effects and timelines vary between individuals. Do not present example effects or timelines as guarantees.

Authoritative source: [Gender-affirming hormone therapy](https://getplume.co/services/gender-affirming-hormone-therapy/).

## Mental health care

Plume publicly describes evaluation, prescription, and ongoing care for:

- anxiety;
- depression;
- insomnia.

Care may include symptom review, standardized screening, medical-history review, clinician evaluation, a treatment plan, medication when appropriate, and follow-up.

Plume is not a crisis service and should not be presented as one.

Authoritative source: [Mental health care](https://getplume.co/services/mental-health/).

## Sexual health care

Plume publicly describes sexual health services for:

- contraception, including options intended to prevent pregnancy or suppress monthly bleeding;
- erectile dysfunction, including care for people using estrogen or other feminizing hormones.

Available treatments depend on clinical evaluation and may vary by state.

Authoritative source: [Sexual health care](https://getplume.co/services/sexual-health/).

## Everyday Care

Plume publicly describes selected everyday care for:

- acne;
- allergies;
- nicotine cessation;
- hair-loss prevention.

These are limited clinical services, not comprehensive primary care. Treatment requires clinician evaluation.

Authoritative source: [Everyday care](https://getplume.co/services/everyday-clinical-services/).

## Gender-transition support

Full Membership includes support related to social, legal, and medical transition goals. Publicly described support may include personalized recommendations, educational resources, and clinician-written support letters.

Plume offers a one-time medical letter-of-support service for surgery. The public pricing page states that behavioral-health letters from a therapist are not currently available through this service. Active members may have eligible support letters included in membership.

Authoritative sources:

- [Services](https://getplume.co/services/)
- [Services and pricing](https://getplume.co/services-pricing/)

## Full Membership

Full Membership is available with monthly, semi-annual (six-month), and annual billing options.

The public pricing page describes Full Membership as including:

- gender-affirming hormone therapy where available;
- mental health, sexual health, and everyday care services offered by Plume;
- the cost, ordering, and analysis of required laboratory work, subject to state rules;
- up to five video appointments per month with a trans-healthcare provider;
- clinician-written prescriptions for gender-affirming medications when clinically appropriate;
- ongoing gender-transition support;
- access to the Prism community;
- support groups, community events, discussion spaces, and educational resources;
- discounts from participating trans- and queer-focused brands.

Medication costs are not included. FSA eligibility depends on the member's FSA administrator.

## Community Membership and Prism

Prism is Plume's private online community for trans and gender-diverse adults. Clinical care is not required to purchase Community Membership.

The public site describes Community Membership as including:

- support groups and community hangouts;
- workshops and trans-focused events;
- community chat and discussion threads;
- educational resources;
- partner discounts.

Community Membership does not include clinical care, prescriptions, or clinician messaging.

Authoritative source: [Plume Community](https://getplume.co/community/).

## Pricing

The following prices were displayed on Plume's public pricing page when this file was reviewed on 2026-08-26:

- Full Membership, monthly: **$99 per month**, with no long-term commitment.
- Full Membership, semi-annual: **$449 billed every six months**, shown as approximately $75 per month.
- Full Membership, annual: **$749 billed annually**, shown as approximately $63 per month.
- Community Membership: **$5 per month**.
- One-time letter-of-support service for non-members: **$150**.

Prescription costs are not included. Services, pricing, laboratory coverage, and age requirements may depend on state restrictions. Always verify current pricing before quoting it.

Authoritative source: [Services and pricing](https://getplume.co/services-pricing/).

## Getting started

A typical public-facing Full Membership flow is:

1. Confirm age, state, and service eligibility.
2. Select a membership plan.
3. Complete intake forms and schedule an appointment.
4. Access Prism, the private community.
5. Meet with a licensed clinician to discuss goals and health history.
6. Develop a care plan.
7. Receive a prescription if the clinician determines that it is appropriate.
8. Complete laboratory work and follow-up care when required.

A prescription should never be described as guaranteed at signup or after payment.

Authoritative source: [How Plume Clinic works](https://getplume.co/how-it-works/).

## State availability

The state list used for this file distinguishes between locations offering both estrogen-based and testosterone-based hormone therapy and locations listing estrogen-based therapy only. Availability can change, so the [current Plume map](https://getplume.co/map/) and state-specific pages are authoritative.

### Estrogen-based and testosterone-based hormone therapy listed

- Arizona
- California
- Colorado
- Florida
- Georgia
- Idaho
- Illinois
- Iowa
- Kansas
- Kentucky
- Maine
- Maryland
- Massachusetts
- Michigan
- Missouri
- Nebraska
- Nevada
- New Jersey
- New Mexico
- New York
- North Carolina
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Tennessee
- Texas
- Vermont
- Virginia
- Washington
- Washington DC
- Wisconsin
- Wyoming

### Estrogen-based hormone therapy only listed

- Alabama
- Alaska
- Arkansas
- Connecticut
- Delaware
- Indiana
- Louisiana
- Minnesota
- Montana
- New Hampshire
- North Dakota
- Rhode Island
- South Dakota
- Utah
- West Virginia

### Not specified by the source availability list

- Hawaii
- Mississippi
- South Carolina

Do not describe Plume as unavailable in an unspecified state without checking the current map. “Not specified” means only that the source list used to prepare this document did not state an availability category.

## Community and educational content

Plume publishes educational and community material for transgender, nonbinary, and gender-diverse audiences. Blog articles may provide useful background but should not override current service, pricing, eligibility, or clinical-policy pages.

- [Plume blog](https://getplume.co/blog/)
- [Support Center](https://support.getplume.co/support/home)
- [Support solutions and FAQs](https://support.getplume.co/support/solutions/)
- [Community](https://getplume.co/community/)

## Source priority

When sources conflict or information may have changed, use them in this order:

1. The relevant current state page or current clinical-service page.
2. The current services-and-pricing page.
3. The Plume Support Center.
4. This file.
5. Older blog posts, press releases, or third-party descriptions.

## Primary public sources

- [Plume Clinic home](https://getplume.co/)
- [About Plume](https://getplume.co/about-us/)
- [Services](https://getplume.co/services/)
- [Gender-affirming hormone therapy](https://getplume.co/services/gender-affirming-hormone-therapy/)
- [Mental health care](https://getplume.co/services/mental-health/)
- [Sexual health care](https://getplume.co/services/sexual-health/)
- [Everyday care](https://getplume.co/services/everyday-clinical-services/)
- [How it works](https://getplume.co/how-it-works/)
- [Services and pricing](https://getplume.co/services-pricing/)
- [Service availability map](https://getplume.co/map/)
- [Community](https://getplume.co/community/)
- [Support Center](https://support.getplume.co/support/home)
- [Support solutions and FAQs](https://support.getplume.co/support/solutions/)
- [XML sitemap](https://getplume.co/sitemap.xml)